Dorothy M Supp Selected Research

Artificial Skin

1/2020	Exogenous Keratinocyte Growth Factor Is Not Required for Pigmentation of Skin Substitutes with Three Isogeneic Cell Types.
1/2020	Light or Dark Pigmentation of Engineered Skin Substitutes Containing Melanocytes Protects Against Ultraviolet Light-Induced DNA Damage In Vivo.
1/2019	Identification of Merkel cells associated with neurons in engineered skin substitutes after grafting to full thickness wounds.
1/2017	Restoration of cutaneous pigmentation by transplantation to mice of isogeneic human melanocytes in dermal-epidermal engineered skin substitutes.
12/2016	Soluble Epoxide Hydrolase Inhibition and Epoxyeicosatrienoic Acid Treatment Improve Vascularization of Engineered Skin Substitutes.
1/2015	Tumorigenicity Testing in Athymic Mice of Cultured Human Melanocytes for Transplantation in Engineered Skin Substitutes.
1/2013	Characterization of hair follicle development in engineered skin substitutes.
10/2012	Morphogenesis of chimeric hair follicles in engineered skin substitutes with human keratinocytes and murine dermal papilla cells.
7/2012	Assessment of replication rates of human keratinocytes in engineered skin substitutes grafted to athymic mice.
6/2012	Deep and superficial keloid fibroblasts contribute differentially to tissue phenotype in a novel in vivo model of keloid scar.

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Dorothy M Supp Research Topics

Disease

30	Burns 01/2022 - 06/2002
30	Wounds and Injuries (Trauma) 11/2020 - 01/2002
16	Cicatrix (Scar) 01/2021 - 07/2011
8	Keloid 01/2020 - 07/2011
5	Inflammation (Inflammations) 01/2022 - 01/2017
3	Erythema 01/2020 - 01/2017
3	Infections 11/2014 - 05/2005
1	COVID-19 01/2022
1	Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome) 01/2022
1	Sepsis (Septicemia) 01/2021
1	Hypopigmentation (Hypomelanosis) 01/2020
1	Ulcer 01/2020
1	Atopic Dermatitis (Atopic Eczema) 01/2020
1	Epidermolysis Bullosa Dystrophica (Dystrophic Epidermolysis Bullosa) 09/2019
1	Pruritus (Itching) 01/2018
1	Vitamin D Deficiency 11/2017
1	Neoplasms (Cancer) 11/2017
1	Fibrosis (Cirrhosis) 11/2017
1	Hypertrophic Cicatrix (Hypertrophic Scar) 01/2017
1	Surgical Wound 12/2016
1	Wound Infection (Wound Infections) 07/2008
1	Muscular Atrophy (Muscle Atrophy) 10/2007

Drug/Important Bio-Agent (IBA)

7	Biopolymers (Biopolymer)IBA 01/2019 - 06/2002
5	Proteins (Proteins, Gene)FDA Link 11/2020 - 07/2013
4	CollagenIBA 09/2019 - 03/2008
4	Biological ProductsIBA 10/2018 - 07/2011
3	Hyaluronan SynthasesIBA 01/2020 - 01/2014
2	Interleukin-6 (Interleukin 6)IBA 01/2021 - 01/2016
2	Wnt-5a ProteinIBA 01/2020 - 01/2016
2	Pharmaceutical PreparationsIBA 01/2020 - 11/2009
2	VimentinIBA 01/2020 - 01/2016
2	osteoblast cadherinIBA 01/2020 - 01/2016
2	Transforming Growth Factor beta (TGF-beta)IBA 01/2017 - 01/2016
2	Plasminogen Activator Inhibitor 2IBA 06/2012 - 07/2011
2	beta-DefensinsIBA 01/2007 - 11/2004
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 07/2004 - 01/2002
1	Cytotoxins (Cytolysins)IBA 01/2022
1	Linoleic Acid (Linoleate)IBA 01/2022
1	Urea (Carbamide)FDA LinkGeneric 01/2022
1	LipopolysaccharidesIBA 01/2021
1	salicylhydroxamic acid (SHAM)IBA 01/2021
1	14,15-dihydroxyeicosatrienoic acidIBA 01/2021
1	OxylipinsIBA 01/2021
1	pirfenidoneIBA 01/2020
1	Fibronectins (Fibronectin)IBA 01/2020
1	KinesinsIBA 01/2020
1	Matrix Metalloproteinase 9 (Gelatinase B)IBA 01/2020
1	Coenzyme A (CoA)IBA 10/2018
1	GelatinIBA 10/2018
1	12- (4'- azido- 2'- nitrophenoxy)dodecanoyl- coenzyme AIBA 10/2018
1	dimemorfan (AT 17)IBA 01/2018
1	Carbon DioxideIBA 01/2018
1	Insulin-Like PeptidesIBA 01/2018
1	Calcitriol Receptors (Calcitriol Receptor)IBA 11/2017
1	CalciumIBA 11/2017
1	AntibodiesIBA 11/2017
1	Vitamin D FDA LinkGeneric 11/2017
1	Versicans (Versican)IBA 01/2017
1	DecorinIBA 01/2017
1	Biomarkers (Surrogate Marker)IBA 01/2016
1	Cadherins (E-Cadherin)IBA 01/2016
1	CateninsIBA 01/2016
1	Metalloproteases (Metalloproteinases)IBA 01/2016
1	Unsaturated Fatty Acids (Polyunsaturated Fatty Acids)IBA 11/2014
1	Fish OilsIBA 11/2014
1	Arginine (L-Arginine)FDA Link 11/2014
1	Omega-3 Fatty Acids (Omega 3 Fatty Acids)IBA 11/2014
1	Transcription Factors (Transcription Factor)IBA 07/2013
1	inhibin beta A subunitIBA 06/2012
1	PeriostinIBA 06/2012
1	Transforming Growth Factors (Transforming Growth Factor)IBA 06/2012
1	Collagen Type I (Type I Collagen)IBA 06/2012
1	alpha2 Subunit Collagen Type IIBA 07/2011
1	Plasminogen Activator Inhibitor 1IBA 07/2011
1	Culture MediaIBA 07/2011
1	Anti-Bacterial Agents (Antibiotics)IBA 11/2009
1	CytokinesIBA 07/2008
1	Dexamethasone (Maxidex)FDA LinkGeneric 10/2007
1	Small Interfering RNA (siRNA)IBA 10/2007
1	Glycogen Synthase Kinase 3 betaIBA 10/2007
1	GlucocorticoidsIBA 10/2007
1	EnzymesIBA 10/2007
1	Serine (L-Serine)FDA Link 10/2007
1	SilverIBA 05/2005
1	ActicoatIBA 05/2005
1	SolutionsIBA 05/2005

Therapy/Procedure

21	Artificial Skin 01/2020 - 06/2002
14	Therapeutics 01/2021 - 06/2012
4	Gas Lasers 01/2021 - 01/2017
4	Autologous Transplantation 11/2020 - 01/2017
4	Lasers (Laser) 01/2020 - 09/2015
4	Transplantation 02/2019 - 01/2007
2	Laser Therapy (Surgery, Laser) 01/2020 - 01/2018
1	Dye Lasers 01/2018
1	Aftercare (After-Treatment) 01/2017
1	Biological Dressings 07/2005